ncorporation of nanomaterials and nanostructures into sensors causes remarkable advances in device operation due to sensitivity, selectivity, multiplexed detection capability, and portability. In this study, a nanographene sensor coated with gold nanoparticles and tripeptide Gly–Gly–His was designed for Cu2+ ion detection at low concentrations. Graphene oxide synthesized by the modified Hummer’s method and analyzed by UV–Vis spectrometry, xray diffraction (XRD), and transmission electron microscopy (TEM). The optimum conditions based on the maximum gold loading were evaluated 71 min for incubation time and 1 for HAuCl4/HEPES concentration ratio. Gold-coating on graphene oxide was approved by TEM, UV– vis spectrometry, XRD, and FTIR. The EDC/Sulfo-NHS method was used to stabilize Gly-Gly-His to graphene oxide-gold, which has a high affinity toward Cu. The performance mechanism of this nano system was based on the localized surface plasmon resonance (LSPR) property of gold nanoparticles. The sensor was extremely selective and sensitive to Cu2+ with the detection limit of 8.83 nM without cross-binding to other metal ions. The response time was evaluated about 9 min. The GO-Au-GGH biosensor was also very stable and easily reused, which further confirms it as an efficient and sensitive Cu2+ ion detection device.
EDUCATION: University of Oslo-Norway| 2016 – 2017 Researcher in Nano-Biotechnology University of Tehran-Iran| 2011 – 2016 PhD in Cellular and Molecular Biology- Biophysics University of Alzahra-Iran| 2007 – 2011 M.Sc. in Microbiology University of Tehran-Iran| 2007 – 2011 B.Sc. in Microbiology EXPERIENCE: Diversified professional with 12+ years in Pharmaceutical and Biological Product Development, 264 Citations with h-index of 7 and 31 Peer-reviewed scientific Publications. Achieved Research Funding and Grants of “Significant Research Funding: Elite Scholarship, University of Tehran”. Lab Manager, Cleanroom manager and QA Specialist at Renap Co. (https://renap.ir). Biotechnology department Manager at Histogenotech Co. (https:// histogene.co). Biology Production Manager at Accelerators and incubators of Paya Fan YakhtehAlborz (https:// celltechco.com/). Assistant professor in: Islamic Azad University, Tehran Medical Branch, Farzanegan Semnan University, Shahed University
Share this page on your timeline